Research · refreshed nightly · July 28, 2026
Great Businesses Facing Disruption (July 2026)
Strong businesses facing real disruption.
A moat is only proven when someone attacks it. The fifty companies here score as great businesses facing disruption, still strong under real competitive pressure, ranked by overall MGI. BillionToOne leads at 77, Alnylam Pharmaceuticals follows at 76 on a $44B cap, and Sweden's Plejd scores 75 while growing per-share revenue 27% a year.
This is not a distress list; a median MGI of 70 would be respectable anywhere on our site. The better way to read it is as a set of live experiments, where each thesis hinges on whether the defense holds. That makes the filings, not the headline score, the interesting part. Click any name for the full citation-backed analysis.
50companies qualify
71median MGI
21joined this week
The ranking
Sorted by MGI
1
BillionToOne, Inc.BLLN🇺🇸
Revenue +70%/yr · +18%/yr per share · asset light
G 77V 54O 79Cap $5.9B
MGI
77
MVI
54
MTI
50
MOI
79
Cap
$5.9B
Growth
+141%2
Alnylam Pharmaceuticals, Inc.ALNY🇺🇸
Revenue +38%/yr · +35%/yr per share · asset light
G 76V 58O 80Cap $40.7B
MGI
76
MVI
58
MTI
42
MOI
80
Cap
$40.7B
Growth
+96%3
Goodwin PLCGDWN.GB🇬🇧
Revenue +13%/yr · +13%/yr per share · scale economics
G 76V 59O 80Cap $2.0B
MGI
76
MVI
59
MTI
29
MOI
80
Cap
$2.0B
Growth
+15%4
Plejd ABPLEJD.SE🇸🇪
Revenue +28%/yr · +27%/yr per share · asset light
G 75V 69O 81Cap $835.1M
MGI
75
MVI
69
MTI
35
MOI
81
Cap
$835.1M
Growth
+28%5
Credo Technology Group Holding LtdCRDO🇺🇸
Revenue +80%/yr · +48%/yr per share · asset light
G 75V 54O 76Cap $36.5B
MGI
75
MVI
54
MTI
57
MOI
76
Cap
$36.5B
Growth
+80%6
Veeva Systems Inc.VEEV🇺🇸
Revenue +14%/yr · +13%/yr per share · asset light
G 75V 68O 87Cap $28.5B
MGI
75
MVI
68
MTI
37
MOI
87
Cap
$28.5B
Growth
+14%7
Ascendis Pharma A/SASND🇩🇰
Revenue +157%/yr · +150%/yr per share · asset light
G 75V 58O 78Cap $16.4B
MGI
75
MVI
58
MTI
43
MOI
78
Cap
$16.4B
Growth
+144%8
Samsara Inc.IOT🇺🇸
Revenue +36%/yr · +14%/yr per share · asset light
G 74V 56O 77Cap $19.2B
MGI
74
MVI
56
MTI
40
MOI
77
Cap
$19.2B
Growth
+31%9
SN
Synektik S.A.SNT.PL🇵🇱
Revenue +35%/yr · +35%/yr per share · asset light
G 73V 64O 78Cap $657.1M
MGI
73
MVI
64
MTI
46
MOI
78
Cap
$657.1M
Growth
+35%10
Shopify Inc.SHOP🇨🇦
Revenue +22%/yr · +21%/yr per share · scale economics
G 73V 51O 74Cap $159.5B
MGI
73
MVI
51
MTI
38
MOI
74
Cap
$159.5B
Growth
+34%11
Astera Labs, Inc.ALAB🇺🇸
Revenue +105%/yr · +21%/yr per share · asset light
G 73V 43O 70Cap $48.4B
MGI
73
MVI
43
MTI
55
MOI
70
Cap
$48.4B
Growth
+93%12
Vitalhub Corp.VHI.CA🇨🇦
Revenue +37%/yr · +23%/yr per share · asset light
G 73V 71O 80Cap $309.8M
MGI
73
MVI
71
MTI
28
MOI
80
Cap
$309.8M
Growth
+47%13
MercadoLibre, Inc.MELI🇺🇾
Revenue +35%/yr · +35%/yr per share · scale economics
G 73V 72O 84Cap $90.0B
MGI
73
MVI
72
MTI
38
MOI
84
Cap
$90.0B
Growth
+49%14
Atlassian CorporationTEAM🇦🇺
Revenue +21%/yr · +20%/yr per share · asset light
G 73V 75O 82Cap $20.9B
MGI
73
MVI
75
MTI
44
MOI
82
Cap
$20.9B
Growth
+32%15
AppLovin CorporationAPP🇺🇸
Revenue +17%/yr · +17%/yr per share · asset light
G 72V 58O 76Cap $136.2B
MGI
72
MVI
58
MTI
60
MOI
76
Cap
$136.2B
Growth
+24%16
Caris Life Sciences, Inc.CAI🇺🇸
Revenue +44%/yr · -24%/yr per share · asset light
G 72V 62O 77Cap $4.7B
MGI
72
MVI
62
MTI
45
MOI
77
Cap
$4.7B
Growth
+79%17
Atour Lifestyle Holdings LtdATAT🇨🇳
Revenue +38%/yr · +31%/yr per share · scale economics
G 72V 66O 80Cap $4.6B
MGI
72
MVI
66
MTI
42
MOI
80
Cap
$4.6B
Growth
+48%18
HEICO CorporationHEI🇺🇸
Revenue +21%/yr · +21%/yr per share · scale economics
G 72V 51O 73Cap $43.8B
MGI
72
MVI
51
MTI
28
MOI
73
Cap
$43.8B
Growth
+25%19
Insulet CorporationPODD🇺🇸
Revenue +21%/yr · +21%/yr per share · asset light
G 72V 62O 78Cap $13.0B
MGI
72
MVI
62
MTI
37
MOI
78
Cap
$13.0B
Growth
+34%20
Zscaler, Inc.ZS🇺🇸
Revenue +33%/yr · +29%/yr per share · asset light
G 71V 64O 76Cap $22.5B
MGI
71
MVI
64
MTI
46
MOI
76
Cap
$22.5B
Growth
+25%21
Sectra ABSECT.B.SE🇸🇪
Revenue +15%/yr · +15%/yr per share · asset light
G 71V 52O 72Cap $4.9B
MGI
71
MVI
52
MTI
28
MOI
72
Cap
$4.9B
Growth
+13%22
Frequentis AGFQT.AT🇦🇹
Revenue +14%/yr · +14%/yr per share · asset light
G 71V 70O 79Cap $1.1B
MGI
71
MVI
70
MTI
35
MOI
79
Cap
$1.1B
Growth
+21%23
argenx SEARGX🇳🇱
Revenue +58%/yr · +50%/yr per share · asset light
G 71V 57O 74Cap $56.6B
MGI
71
MVI
57
MTI
43
MOI
74
Cap
$56.6B
Growth
+64%24
Lotus Bakeries NVLOTB.BE🇧🇪
Revenue +15%/yr · +15%/yr per share · asset light
G 71V 48O 70Cap $8.6B
MGI
71
MVI
48
MTI
33
MOI
70
Cap
$8.6B
Growth
+10%25
ServiceTitan, Inc.TTAN🇺🇸
Revenue +20%/yr · -15%/yr per share · asset light
G 71V 66O 78Cap $6.4B
MGI
71
MVI
66
MTI
42
MOI
78
Cap
$6.4B
Growth
+25%26
Guidewire Software, Inc.GWRE🇺🇸
Revenue +14%/yr · +13%/yr per share · asset light
G 71V 64O 79Cap $12.1B
MGI
71
MVI
64
MTI
32
MOI
79
Cap
$12.1B
Growth
+27%27
Triple Flag Precious Metals Corp.TFPM🇨🇦
Revenue +25%/yr · +17%/yr per share · asset light
G 71V 58O 74Cap $6.0B
MGI
71
MVI
58
MTI
37
MOI
74
Cap
$6.0B
Growth
+79%28
United Therapeutics CorporationUTHR🇺🇸
Revenue +13%/yr · +13%/yr per share · asset light
G 70V 52O 71Cap $25.6B
MGI
70
MVI
52
MTI
55
MOI
71
Cap
$25.6B
Growth
-2%29
Reddit, Inc.RDDT🇺🇸
Revenue +39%/yr · +5%/yr per share · asset light
G 70V 69O 75Cap $30.2B
MGI
70
MVI
69
MTI
48
MOI
75
Cap
$30.2B
Growth
+69%30
Natera, Inc.NTRA🇺🇸
Revenue +32%/yr · +21%/yr per share · asset light
G 70V 57O 73Cap $32.7B
MGI
70
MVI
57
MTI
45
MOI
73
Cap
$32.7B
Growth
+32%31
Diploma PLCDPLM.GB🇬🇧
Revenue +15%/yr · +13%/yr per share · scale economics
G 70V 55O 73Cap $12.1B
MGI
70
MVI
55
MTI
37
MOI
73
Cap
$12.1B
Growth
+12%32
Rubrik, Inc.RBRK🇺🇸
Revenue +34%/yr · -35%/yr per share · asset light
G 70V 57O 73Cap $15.4B
MGI
70
MVI
57
MTI
44
MOI
73
Cap
$15.4B
Growth
+39%33
FOPE S.p.A.FPE.IT🇮🇹
Revenue +27%/yr · +26%/yr per share · asset light
G 70V 63O 74Cap $242.5M
MGI
70
MVI
63
MTI
42
MOI
74
Cap
$242.5M
Growth
+27%34
Texas Pacific Land CorporationTPL🇺🇸
Revenue +13%/yr · +13%/yr per share · asset light
G 70V 45O 67Cap $30.0B
MGI
70
MVI
45
MTI
40
MOI
67
Cap
$30.0B
Growth
+21%35
Kuros Biosciences LtdKURN.CH🇨🇭
Revenue +101%/yr · +80%/yr per share · asset light
G 70V 59O 74Cap $1.0B
MGI
70
MVI
59
MTI
43
MOI
74
Cap
$1.0B
Growth
+72%36
Eagle Eye Solutions Group plcEYE.GB🇬🇧
Revenue +17%/yr · +11%/yr per share · asset light
G 70V 67O 75Cap $196.6M
MGI
70
MVI
67
MTI
42
MOI
75
Cap
$196.6M
Growth
+11%37
Global-E Online Ltd.GLBE🇮🇱
Revenue +33%/yr · +19%/yr per share · scale economics
G 70V 66O 76Cap $5.8B
MGI
70
MVI
66
MTI
45
MOI
76
Cap
$5.8B
Growth
+33%38
Grab Holdings LimitedGRAB🇸🇬
Revenue +39%/yr · -8%/yr per share · scale economics
G 70V 63O 75Cap $14.3B
MGI
70
MVI
63
MTI
46
MOI
75
Cap
$14.3B
Growth
+24%39
ASM International N.V.ASM.NL🇳🇱
Revenue +13%/yr · +13%/yr per share · asset light
G 70V 42O 67Cap $39.9B
MGI
70
MVI
42
MTI
44
MOI
67
Cap
$39.9B
Growth
+7%40
On Holding AGONON🇨🇭
Revenue +34%/yr · +28%/yr per share · asset light
G 70V 63O 75Cap $13.1B
MGI
70
MVI
63
MTI
40
MOI
75
Cap
$13.1B
Growth
+34%41
Constellation Software Inc.CSU.CA🇨🇦
Revenue +19%/yr · +19%/yr per share · scale economics
G 70V 60O 75Cap $47.1B
MGI
70
MVI
60
MTI
38
MOI
75
Cap
$47.1B
Growth
+20%42
Pure Cycle CorporationPCYO🇺🇸
Revenue +18%/yr · +18%/yr per share · scale economics
G 70V 59O 72Cap $257.3M
MGI
70
MVI
59
MTI
28
MOI
72
Cap
$257.3M
Growth
+60%43
TWFG, Inc.TWFG🇺🇸
Revenue +16%/yr · -70%/yr per share · scale economics
G 70V 77O 78Cap $303M
MGI
70
MVI
77
MTI
43
MOI
78
Cap
$303M
Growth
+36%44
Vericel CorporationVCEL🇺🇸
Revenue +13%/yr · +11%/yr per share · asset light
G 70V 55O 72Cap $2.3B
MGI
70
MVI
55
MTI
28
MOI
72
Cap
$2.3B
Growth
+30%45
Hamilton Lane IncorporatedHLNE🇺🇸
Revenue +15%/yr · +7%/yr per share · asset light
G 69V 63O 73Cap $4.6B
MGI
69
MVI
63
MTI
43
MOI
73
Cap
$4.6B
Growth
-2%46
CAVA Group, Inc.CAVA🇺🇸
Revenue +21%/yr · -56%/yr per share · asset light
G 69V 44O 67Cap $7.5B
MGI
69
MVI
44
MTI
38
MOI
67
Cap
$7.5B
Growth
+93%47
Bentley Systems, IncorporatedBSY🇺🇸
Revenue +10%/yr · +9%/yr per share · asset light
G 69V 57O 72Cap $10.5B
MGI
69
MVI
57
MTI
38
MOI
72
Cap
$10.5B
Growth
+15%48
Tradeweb Markets Inc.TW🇺🇸
Revenue +15%/yr · +14%/yr per share · asset light
G 69V 64O 77Cap $23.6B
MGI
69
MVI
64
MTI
40
MOI
77
Cap
$23.6B
Growth
+21%
Changed this week
Week over week, from the nightly refresh.
Entered
Hamilton Lane Incorporated (HLNE) · joined at #45 · Revenue +15%/yr · +7%/yr per share · asset light
EnteredAtriCure, Inc. (ATRC) · joined at #50 · Revenue +16%/yr · +14%/yr per share · asset light
EnteredFrequentis AG (FQT.AT) · joined at #22 · Revenue +14%/yr · +14%/yr per share · asset light
EnteredGlobal-E Online Ltd. (GLBE) · joined at #37 · Revenue +33%/yr · +19%/yr per share · scale economics
EnteredTWFG, Inc. (TWFG) · joined at #43 · Revenue +16%/yr · -70%/yr per share · scale economics
+7 more
APP, ARGX, HLNE, CAVA, BSY, TW, GDWN.GB also joined
Left
TNIE.DE, WSE, R3NK.DE, HLNE, RHM.DE, LAGR.B.SE, NOW, ANET, BKNG, CRWD, LB, FROG
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Research tool, not investment advice. Rankings are generated by our models from company filings and market data, refresh nightly, and are identical for every visitor. Scores reflect our methodology and are not recommendations to act. Data as of 2026-07-28.