Research · refreshed nightly · August 17, 2026
Great Businesses Facing Disruption (October 2026)
Strong businesses facing real disruption.
A moat is only proven when someone attacks it. The fifty companies here score as great businesses facing disruption, still strong under real competitive pressure, ranked by overall MGI. BillionToOne leads at 77, Alnylam Pharmaceuticals follows at 76 on a $44B cap, and Sweden's Plejd scores 75 while growing per-share revenue 27% a year.
This is not a distress list; a median MGI of 70 would be respectable anywhere on our site. The better way to read it is as a set of live experiments, where each thesis hinges on whether the defense holds. That makes the filings, not the headline score, the interesting part. Click any name for the full citation-backed analysis.
50companies qualify
71median MGI
0joined this week
The ranking
Sorted by MGI
1
BillionToOne, Inc.BLLN🇺🇸
Revenue +77%/yr · +10%/yr per share · asset light
G 77V 58O 81Cap $5.0B
MGI
77
MVI
58
MTI
50
MOI
81
Cap
$5.0B
Growth
+64%2
Goodwin PLCGDWN.GB🇬🇧
Revenue +13%/yr · +13%/yr per share · scale economics
G 76V 58O 79Cap $2.1B
MGI
76
MVI
58
MTI
29
MOI
79
Cap
$2.1B
Growth
+15%3
Plejd ABPLEJD.SE🇸🇪
Revenue +28%/yr · +27%/yr per share · asset light
G 75V 68O 81Cap $858.6M
MGI
75
MVI
68
MTI
35
MOI
81
Cap
$858.6M
Growth
+28%4
Veeva Systems Inc.VEEV🇺🇸
Revenue +14%/yr · +13%/yr per share · asset light
G 75V 60O 83Cap $39.6B
MGI
75
MVI
60
MTI
37
MOI
83
Cap
$39.6B
Growth
+14%5
Ascendis Pharma A/SASND🇩🇰
Revenue +167%/yr · +159%/yr per share · asset light
G 75V 55O 77Cap $18.3B
MGI
75
MVI
55
MTI
43
MOI
77
Cap
$18.3B
Growth
+144%6
Credo Technology Group Holding LtdCRDO🇺🇸
Revenue +80%/yr · +48%/yr per share · asset light
G 75V 46O 73Cap $48.5B
MGI
75
MVI
46
MTI
57
MOI
73
Cap
$48.5B
Growth
+157%7
Reddit, Inc.RDDT🇺🇸
Revenue +42%/yr · +8%/yr per share · asset light
G 74V 62O 77Cap $33.8B
MGI
74
MVI
62
MTI
45
MOI
77
Cap
$33.8B
Growth
+61%8
Arm Holdings plcARM🇬🇧
Revenue +21%/yr · +20%/yr per share · asset light
G 74V 33O 65Cap $338.6B
MGI
74
MVI
33
MTI
46
MOI
65
Cap
$338.6B
Growth
+22%9
Samsara Inc.IOT🇺🇸
Revenue +36%/yr · +14%/yr per share · asset light
G 74V 54O 76Cap $20.5B
MGI
74
MVI
54
MTI
40
MOI
76
Cap
$20.5B
Growth
+31%10
Amphenol CorporationAPH🇺🇸
Revenue +22%/yr · +21%/yr per share · scale economics
G 74V 50O 74Cap $211.7B
MGI
74
MVI
50
MTI
38
MOI
74
Cap
$211.7B
Growth
+58%11
Vitalhub Corp.VHI.CA🇨🇦
Revenue +39%/yr · +24%/yr per share · asset light
G 73V 69O 79Cap $343M
MGI
73
MVI
69
MTI
28
MOI
79
Cap
$343M
Growth
+33%12
Astera Labs, Inc.ALAB🇺🇸
Revenue +118%/yr · +29%/yr per share · asset light
G 73V 39O 68Cap $55.8B
MGI
73
MVI
39
MTI
55
MOI
68
Cap
$55.8B
Growth
+105%13
Shopify Inc.SHOP🇨🇦
Revenue +24%/yr · +23%/yr per share · scale economics
G 73V 49O 72Cap $173.9B
MGI
73
MVI
49
MTI
38
MOI
72
Cap
$173.9B
Growth
+34%14
Alnylam Pharmaceuticals, Inc.ALNY🇺🇸
Revenue +42%/yr · +37%/yr per share · asset light
G 73V 59O 77Cap $35.4B
MGI
73
MVI
59
MTI
40
MOI
77
Cap
$35.4B
Growth
+67%15
Atlassian CorporationTEAM🇦🇺
Revenue +22%/yr · +21%/yr per share · asset light
G 73V 58O 76Cap $41.2B
MGI
73
MVI
58
MTI
44
MOI
76
Cap
$41.2B
Growth
+20%16
MercadoLibre, Inc.MELI🇺🇾
Revenue +38%/yr · +37%/yr per share · scale economics
G 73V 72O 84Cap $89.8B
MGI
73
MVI
72
MTI
38
MOI
84
Cap
$89.8B
Growth
+50%17
SN
Synektik S.A.SNT.PL🇵🇱
Revenue +48%/yr · +48%/yr per share · scale economics
G 73V 60O 76Cap $764M
MGI
73
MVI
60
MTI
46
MOI
76
Cap
$764M
Growth
+48%18
Atour Lifestyle Holdings LtdATAT🇨🇳
Revenue +38%/yr · +31%/yr per share · scale economics
G 72V 66O 79Cap $4.7B
MGI
72
MVI
66
MTI
42
MOI
79
Cap
$4.7B
Growth
+48%19
HEICO CorporationHEI🇺🇸
Revenue +21%/yr · +21%/yr per share · scale economics
G 72V 51O 72Cap $45.0B
MGI
72
MVI
51
MTI
28
MOI
72
Cap
$45.0B
Growth
+25%20
Caris Life Sciences, Inc.CAI🇺🇸
Revenue +48%/yr · -27%/yr per share · asset light
G 72V 58O 75Cap $5.6B
MGI
72
MVI
58
MTI
45
MOI
75
Cap
$5.6B
Growth
+45%21
AppLovin CorporationAPP🇺🇸
Revenue +20%/yr · +20%/yr per share · asset light
G 72V 65O 79Cap $106.0B
MGI
72
MVI
65
MTI
60
MOI
79
Cap
$106.0B
Growth
+24%22
Insulet CorporationPODD🇺🇸
Revenue +23%/yr · +22%/yr per share · asset light
G 72V 68O 80Cap $10.2B
MGI
72
MVI
68
MTI
37
MOI
80
Cap
$10.2B
Growth
+24%23
Lotus Bakeries NVLOTB.BE🇧🇪
Revenue +14%/yr · +14%/yr per share · asset light
G 71V 41O 66Cap $11.3B
MGI
71
MVI
41
MTI
33
MOI
66
Cap
$11.3B
Growth
+10%24
Sectra ABSECT.B.SE🇸🇪
Revenue +15%/yr · +15%/yr per share · asset light
G 71V 52O 71Cap $5.0B
MGI
71
MVI
52
MTI
28
MOI
71
Cap
$5.0B
Growth
+13%25
Triple Flag Precious Metals Corp.TFPM🇨🇦
Revenue +27%/yr · +18%/yr per share · asset light
G 71V 51O 71Cap $7.6B
MGI
71
MVI
51
MTI
37
MOI
71
Cap
$7.6B
Growth
+37%26
ServiceTitan, Inc.TTAN🇺🇸
Revenue +20%/yr · -15%/yr per share · asset light
G 71V 58O 75Cap $8.6B
MGI
71
MVI
58
MTI
42
MOI
75
Cap
$8.6B
Growth
+25%27
Guidewire Software, Inc.GWRE🇺🇸
Revenue +14%/yr · +13%/yr per share · asset light
G 71V 61O 78Cap $13.2B
MGI
71
MVI
61
MTI
32
MOI
78
Cap
$13.2B
Growth
+27%28
Zscaler, Inc.ZS🇺🇸
Revenue +33%/yr · +29%/yr per share · asset light
G 71V 56O 73Cap $29.7B
MGI
71
MVI
56
MTI
46
MOI
73
Cap
$29.7B
Growth
+25%29
DexCom, Inc.DXCM🇺🇸
Revenue +15%/yr · +17%/yr per share · asset light
G 71V 58O 75Cap $29.6B
MGI
71
MVI
58
MTI
46
MOI
75
Cap
$29.6B
Growth
+13%30
argenx SEARGX🇳🇱
Revenue +58%/yr · +50%/yr per share · asset light
G 71V 57O 74Cap $55.6B
MGI
71
MVI
57
MTI
43
MOI
74
Cap
$55.6B
Growth
+60%31
Frequentis AGFQT.AT🇦🇹
Revenue +15%/yr · +15%/yr per share · asset light
G 71V 72O 80Cap $994M
MGI
71
MVI
72
MTI
35
MOI
80
Cap
$994M
Growth
+21%32
Tradeweb Markets Inc.TW🇺🇸
Revenue +15%/yr · +15%/yr per share · asset light
G 71V 57O 74Cap $22.1B
MGI
71
MVI
57
MTI
48
MOI
74
Cap
$22.1B
Growth
+9%33
AL
Allegro.eu S.A.ALE.PL🇵🇱
Revenue +17%/yr · +17%/yr per share · asset light
G 70V 75O 78Cap $7.2B
MGI
70
MVI
75
MTI
44
MOI
78
Cap
$7.2B
Growth
+17%34
FOPE S.p.A.FPE.IT🇮🇹
Revenue +27%/yr · +26%/yr per share · asset light
G 70V 62O 74Cap $247.5M
MGI
70
MVI
62
MTI
42
MOI
74
Cap
$247.5M
Growth
+27%35
Texas Pacific Land CorporationTPL🇺🇸
Revenue +15%/yr · +15%/yr per share · asset light
G 70V 47O 69Cap $27.5B
MGI
70
MVI
47
MTI
40
MOI
69
Cap
$27.5B
Growth
+31%36
Eagle Eye Solutions Group plcEYE.GB🇬🇧
Revenue +17%/yr · +11%/yr per share · asset light
G 70V 66O 75Cap $203.5M
MGI
70
MVI
66
MTI
42
MOI
75
Cap
$203.5M
Growth
+11%37
Global-E Online Ltd.GLBE🇮🇱
Revenue +35%/yr · +21%/yr per share · scale economics
G 70V 63O 75Cap $6.5B
MGI
70
MVI
63
MTI
45
MOI
75
Cap
$6.5B
Growth
+33%38
Diploma PLCDPLM.GB🇬🇧
Revenue +15%/yr · +13%/yr per share · scale economics
G 70V 55O 73Cap $12.1B
MGI
70
MVI
55
MTI
37
MOI
73
Cap
$12.1B
Growth
+12%39
Grab Holdings LimitedGRAB🇸🇬
Revenue +41%/yr · -7%/yr per share · scale economics
G 70V 62O 75Cap $15.1B
MGI
70
MVI
62
MTI
46
MOI
75
Cap
$15.1B
Growth
+22%40
ASM International N.V.ASM.NL🇳🇱
Revenue +14%/yr · +14%/yr per share · asset light
G 70V 45O 68Cap $53.8B
MGI
70
MVI
45
MTI
42
MOI
68
Cap
$53.8B
Growth
+7%41
On Holding AGONON🇨🇭
Revenue +35%/yr · +31%/yr per share · asset light
G 70V 64O 75Cap $12.7B
MGI
70
MVI
64
MTI
40
MOI
75
Cap
$12.7B
Growth
+35%42
Constellation Software Inc.CSU.CA🇨🇦
Revenue +20%/yr · +20%/yr per share · scale economics
G 70V 57O 74Cap $51.9B
MGI
70
MVI
57
MTI
38
MOI
74
Cap
$51.9B
Growth
+20%43
Pure Cycle CorporationPCYO🇺🇸
Revenue +13%/yr · +13%/yr per share · scale economics
G 70V 59O 72Cap $263.1M
MGI
70
MVI
59
MTI
28
MOI
72
Cap
$263.1M
Growth
+60%44
TWFG, Inc.TWFG🇺🇸
Revenue +20%/yr · -65%/yr per share · scale economics
G 70Cap $1.4B
MGI
70
MTI
43
MOI
Cap
$1.4B
Growth
+36%45
nVent Electric plcNVT🇺🇸
Revenue +14%/yr · +15%/yr per share · scale economics
G 70V 51O 70Cap $27.6B
MGI
70
MVI
51
MTI
43
MOI
70
Cap
$27.6B
Growth
+54%46
Kuros Biosciences LtdKURN.CH🇨🇭
Revenue +63%/yr · +56%/yr per share · asset light
G 70V 58O 73Cap $1.1B
MGI
70
MVI
58
MTI
43
MOI
73
Cap
$1.1B
Growth
+72%47
Rubrik, Inc.RBRK🇺🇸
Revenue +34%/yr · -35%/yr per share · asset light
G 70V 48O 69Cap $21.0B
MGI
70
MVI
48
MTI
44
MOI
69
Cap
$21.0B
Growth
+39%48
United Therapeutics CorporationUTHR🇺🇸
Revenue +13%/yr · +14%/yr per share · asset light
G 70V 56O 72Cap $22.3B
MGI
70
MVI
56
MTI
55
MOI
72
Cap
$22.3B
Growth
-2%
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Research tool, not investment advice. Rankings are generated by our models from company filings and market data, refresh nightly, and are identical for every visitor. Scores reflect our methodology and are not recommendations to act. Data as of 2026-08-17.